Toll-like receptor signaling in transplantation
نویسندگان
چکیده
منابع مشابه
Toll-like receptor downstream signaling
The family of Toll-like receptors (TLRs) senses conserved structures found in a broad range of pathogens, causing innate immune responses that include the production of inflammatory cytokines, chemokines and interferons. The signal transduction is initiated from the Toll/interleukin-1 receptor (TIR) domain of TLRs after pathogen recognition. Almost all TLRs use a TIR-containing adapter MyD88 to...
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1Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA 2Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA 3Department of Molecular Microbiology and Immunology, University of Southern California School of Medicine, Los Angeles, CA 90033, USA 4Malari Program, Seattle Biomedical Research Institute, Seattle, WA 98109, US...
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ژورنال
عنوان ژورنال: Current Opinion in Organ Transplantation
سال: 2008
ISSN: 1087-2418
DOI: 10.1097/mot.0b013e3283061149